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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MITF All Species: 18.48
Human Site: S516 Identified Species: 67.78
UniProt: O75030 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75030 NP_000239.1 526 58795 S516 K T S S R R S S M S M E E T E
Chimpanzee Pan troglodytes A2T713 347 38902 S338 K E S S R R S S F S S D D G D
Rhesus Macaque Macaca mulatta XP_001086622 526 58747 S516 K T S S R R S S M S M E E T E
Dog Lupus familis XP_863779 580 61999 P562 P L L S S V S P A V S K A S S
Cat Felis silvestris
Mouse Mus musculus Q08874 526 58609 S516 K T S S R R S S M S A E E T E
Rat Rattus norvegicus Q63302 317 35156 S308 S K A S S R S S L S S E D G D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5XFQ6 377 42496 S368 K E S S R R S S F S T D D G D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 38.2 99.8 47.2 N.A. 95.2 33.8 N.A. N.A. 40.1 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 49 99.8 60.1 N.A. 96.9 44.4 N.A. N.A. 53 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 53.3 100 13.3 N.A. 93.3 40 N.A. N.A. 53.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 73.3 100 26.6 N.A. 93.3 66.6 N.A. N.A. 73.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 15 0 0 0 0 0 15 0 15 0 15 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 29 43 0 43 % D
% Glu: 0 29 0 0 0 0 0 0 0 0 0 58 43 0 43 % E
% Phe: 0 0 0 0 0 0 0 0 29 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 43 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 72 15 0 0 0 0 0 0 0 0 0 15 0 0 0 % K
% Leu: 0 15 15 0 0 0 0 0 15 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 43 0 29 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 15 0 0 0 0 0 0 15 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 72 86 0 0 0 0 0 0 0 0 0 % R
% Ser: 15 0 72 100 29 0 100 86 0 86 43 0 0 15 15 % S
% Thr: 0 43 0 0 0 0 0 0 0 0 15 0 0 43 0 % T
% Val: 0 0 0 0 0 15 0 0 0 15 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _